Publications by authors named "H G Clement"
Article Synopsis
- Aripiprazole, a medication approved for severe mental disorders, is often prescribed off-label to children and adolescents, yet there are no established therapeutic serum level reference ranges for this population.
- A study aimed to investigate the relationship between aripiprazole dosage and serum concentrations in youth, identifying factors like sex, age, and weight that might influence these levels.
- The findings suggested a strong correlation between daily dosage and serum concentration, leading to a preliminary reference range for treating pediatric patients, which indicated potentially better outcomes and fewer side effects when using interquartile ranges for dose determination.
A diastereoselective hydrodifluoromethylation of -heteroaryl alkenes was successfully established. This method was applicable to an array of -heteroaryl substrates with both cyclic and acyclic alkenes while displaying tolerance to a variety of functional groups. The conditions were also expanded to obtain hydrotrifluoromethylated products with similar results.
View Article and Find Full Text PDFWetlands perform important functions and provide essential ecological services, including flood attenuation, groundwater recharge and discharge, and water purification. Human activities such as urban and rural development, drainage, and land alteration can cause major disturbances, often resulting in the drying up of wetlands. Therefore, many restoration projects aim to restore wetland hydrology.
View Article and Find Full Text PDFAntivenoms are essential in the treatment of the neurotoxicity caused by elapid snakebites. However, there are elapid neurotoxins, e.g.
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