Vault RNAs (vtRNAs) are a novel group of non-coding RNAs that are involved in various signaling mechanisms. vtRNAs are joined by three proteins major vault protein (MVP), vault poly (ADP-ribose) polymerase (VPARP), and telomerase-associated protein 1 (TEP1) to form the vault complex. In humans, only four vtRNA including vtRNA 1-1, vtRNA 1-2, vtRNA 1-3, vtRNA 2-1) have been discovered.
View Article and Find Full Text PDFBupropion (Bup), an antidepressant, is used to treat depression and aid in quitting smoking. We aim to investigate the influence of Bup on nicotine withdrawal (NW)-associated disturbances in serotonergic neurotransmission and behavior in mice. Adult albino mice were categorized into control and NW groups.
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