Publications by authors named "H F Schirmer"
Background: Noninvasive assessment of elevated filling pressure in the left ventricle (LV) remains an unresolved problem. Of the many echocardiographic parameters used to evaluate diastolic pressure, the left atrial strain and strain rate (LA S/SR) have shown promise in clinical settings. However, only a few previous studies have evaluated LA S/SR in larger populations.
View Article and Find Full Text PDFObjectives: The main objective of this study was twofold: to investigate what kind of information patients with heart failure (HF) tell their doctors about their medication adherence at home, and how often such information is provided in consultations where medication reconciliation is recommended. To meet these objectives, we developed an analysis to recognise, define, and count (1) patient utterances including medication adherence disclosures in clinical interactions (MADICI), (2) MADICI including red-flags for non-adherence, and (3) MADICI initiated by patients without prompts from their doctor.
Design: Exploratory interaction-based observational cohort study.
Article Synopsis
- - The study focused on creating and validating a Loop-mediated Isothermal Amplification (LAMP) assay specifically for detecting Sporothrix brasiliensis, using six primers based on the calmodulin gene.
- - Testing involved twenty S. brasiliensis isolates from humans and animals, as well as tissue samples from infected mice, confirming that all tested samples produced positive results, demonstrating high sensitivity and specificity (100%).
- - The LAMP technique shows promise as a simple and cost-effective method for diagnosing sporotrichosis, with plans for further validation using samples from both humans and animals.
Spousal bereavement is associated with health declines and increased mortality risk, but its specific impact on physical and cognitive capabilities is less studied. A historical cohort study design was applied including married Tromsø study participants (N=5739) aged 50-70 years with baseline self-reported overall health and health-related factors and measured capability (grip strength, finger tapping, digit symbol coding, and short-term recall) at follow-up. Participants had data from Tromsø4 (1994-1995) and Tromsø5 (2001), or Tromsø6 (2007-2008) and Tromsø7 (2015-2016).
View Article and Find Full Text PDFObjectives: Previous studies have suggested that experimental pain sensitivity is associated with cognitive function. The aim of this study is to assess this relationship in a large population-based sample.
Methods: We included 5,753 participants (aged 40-84 years) from the seventh wave of the population-based Tromsø Study who had been examined with cognitive tests and experimental pain assessments, and for whom information on covariates were available.