Disabled bodies have been historically marginalised in sporting arenas and spectacles. Assistive technologies have been increasingly featuring in, and changing, sporting landscapes. In some ways recent shifts have made disability more present and visible across many (para) sporting cultures, and yet sport continues to operate on a tiered system that assumes a normative able body.
View Article and Find Full Text PDFPurpose: Dietary macronutrients significantly impact cardiometabolic health, yet research often focuses on individual macronutrient relationships. This study aimed to explore the associations between dietary macronutrient composition and cardiometabolic health.
Methods: This study included 33,681 US adults (49.
This study reports the process evaluation of a randomized controlled trial of the MyHeartMate app for patients with coronary heart disease (CHD). Data were collected on engagement in the intervention group from the app platform logs and self-reported usage and via interviews for perspectives of usefulness and acceptability. Participants' ( = 194) data logs showed 80.
View Article and Find Full Text PDFExercise testing is frequently incorporated into management of patients with cardiovascular and/or pulmonary disease. A lifelong commitment to exercise promotes cardiac remodeling, leading to changes in structure and function of the atria and ventricles, commonly referred to as the "athletic heart." Stress testing is also incorporated into the management of athletes for a variety of reasons, such as identifying the cause of exertional symptoms, determining level of fitness and training zones, or assessing for acquired cardiomyopathies.
View Article and Find Full Text PDFThe recognition of B-cell prolymphocytic leukemia (B-PLL) as a separate entity is controversial based on the current classification systems. Here, we analyzed the DNA methylome of a cohort of 20 B-PLL cases diagnosed according to the guidelines of the International Consensus Classification/Fourth revised edition of the World Health Organization Classification, and compared them with chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), splenic marginal zone lymphoma (SMZL), and normal B-cell subpopulations. Unsupervised principal component analyses suggest that B-PLL is epigenetically distinct from CLL, MCL, and SMZL, which is further supported by robust differential methylation signatures in B-PLL.
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