Publications by authors named "H F Merk"

Positive patch test responses to benzoyl peroxide (BPO) have been reported from patients without and with known exposure. Up to 6.5% were found in the United States and 7.

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Drug hypersensitivity reactions (DHRs) are a type of adverse drug reaction that can occur with different classes of drugs and affect multiple organ systems and patient populations. DHRs can be classified as allergic or non-allergic based on the cellular mechanisms involved. Whereas nonallergic reactions rely mainly on the innate immune system, allergic reactions involve the generation of an adaptive immune response.

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Article Synopsis
  • Hymenoptera venom (HV), injected by bees and wasps during stings, can cause allergic reactions in about 3% of people, leading to severe local or systemic allergic reactions in some cases.
  • The guidelines suggest that while symptomatic therapy is needed after a severe local reaction, specific allergen immunotherapy isn't necessary unless severe reactions occur beyond the skin.
  • Clinicians should assess patients for risk factors, measure tryptase levels if reactions are significant, and test for specific IgE antibodies to diagnose sensitization to Hymenoptera venom.
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