Publications by authors named "H F Dean"

Assisted dying is available in many countries globally but remains illegal in the UK, where there are ongoing debates about its legal status. Britons seeking an assisted death must travel to Switzerland. This article explores the experiences of UK-based individuals considering an assisted death and family members of those who have completed an assisted death.

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Article Synopsis
  • - 6-Mercaptopurine (6-MP) is commonly used for leukemia and inflammatory bowel disease, but it has serious side effects like gastrointestinal issues and liver toxicity, which can cause patients to stop treatment and increase relapse risk.
  • - Research has identified the SLC43A3 gene, which encodes the ENBT1 transporter responsible for moving 6-MP into human cells, particularly in the gastrointestinal tract, bone marrow, and liver, though its connection to 6-MP side effects is still unclear.
  • - By studying both human and mouse models, findings indicate that the ENBT1 transporter functions similarly in both species, suggesting that mouse models could be useful for understanding how changes in ENBT1 impact
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In our study of 246 newly diagnosed individuals with MGUS or SMM (115 MGUS, 131 SMM), we found that 19% reported anxiety, with no significant difference between the MGUS and SMM groups (22% vs. 17%). Those with a history of psychiatric disorders or belonging to certain racial groups were more likely to experience anxiety.

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The 10th International Brain Computer Interface (BCI) Society Meeting, 'Balancing Innovation and Translation', was held from the 6th to 9th of June 2023 in Brussels, Belgium. This report provides a summary of the workshop 'Building Consensus on Clinical Outcome Assessments (COAs) for BCI Devices'. This workshop was intended to give participants an overview of the current state of BCI, future opportunities, and how different countries and regions provide regulatory oversight to support the BCI community to develop safe and effective devices for patients.

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