Publications by authors named "H Eric L Maw"
Article Synopsis
- - This annual review is the eighth installment in a series that began in 2016, focusing on significant articles in biotransformation research.
- - The review aims to explore and share influential findings that contribute to the field.
- - Each article is summarized with key points, followed by commentary, relevant figures, and references to enhance understanding.
Proper species identification is the keystone of successful integrated pest management (IPM). However, efforts to identify thrips species in Canadian greenhouses have not been formally made since the 1980s. In response to recent increases in crop damage, we sampled thrips communities from eight commercial floriculture greenhouses in the Niagara region (Ontario, Canada) from May until August 2016.
View Article and Find Full Text PDFThis annual review is the eighth of its kind since 2016 (Baillie et al. 2016, Khojasteh et al. 2017, Khojasteh et al.
View Article and Find Full Text PDFArticle Synopsis
- * LC-MS platforms are continually evolving to enhance the accuracy and efficiency of drug analysis, while better reagents and bio-matrices are improving the relevance of sample processing.
- * The integration of modern software, ML, and AI with traditional methods is deepening our understanding of bioactivation pathways, which is crucial for developing better medicines for patients with urgent health needs.
Purpose: After single oral dosing of the glycine reuptake transporter (GlyT1) inhibitor, iclepertin (BI 425809), a single major circulating metabolite, M530a, was identified. However, upon multiple dosing, a second major metabolite, M232, was observed with exposure levels ~ twofold higher than M530a. Studies were conducted to characterize the metabolic pathways and enzymes responsible for formation of both major human metabolites.
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