Publications by authors named "H Erdal"
Background: Maresin-1 (MaR1) is a macrophage-derived antiinflammatory lipid mediator that negatively regulates oxidative and proinflammatory cytokines and also restores integrity in various tissues after inflammation. Non-resolving inflammation is known to have an important role in the pathogenesis of hepatocellular carcinoma (HCC). The aim of the present study was to evaluate the role of MaR1 in pathogenesis and early diagnosis of HCC.
View Article and Find Full Text PDFGestational Oxidative Stress and OGTT: Are Pregnant Women's Fears Justified?
Diabetes Metab Syndr Obes
December 2024
Purpose: Pregnancy induces significant metabolic, immunological, and endocrinological changes to support fetal growth. The 75-gram oral glucose tolerance test (OGTT) is standard for gestational diabetes screening, but concerns exist about its potential to induce oxidative stress, affecting both maternal and fetal health. The aim of the study is examining changes in oxidative stress markers and thiol/disulfide homeostasis in pregnant women to evaluate these concerns.
View Article and Find Full Text PDFArticle Synopsis
- The rapid diagnosis of anaerobic bacteria is vital in clinical microbiology, and automatic jar gassing systems are crucial for this process.
- The study aims to create a new jar gassing system that uses a real-time algorithm to improve performance by accurately estimating reaction rates in the palladium/alumina catalyst.
- The research demonstrates high effectiveness with various bacterial strains, validating the engineering approach and providing detailed insights into catalyst behavior and system performance.
Article Synopsis
- Neurodegenerative disorders involve neuroinflammation, and this study used lipopolysaccharide (LPS) to induce neuroinflammation in animal models, simulating cognitive impairment.
- The experiment involved injecting LPS and testing the effects of Adalimumab (a TNF-α inhibitor) and curcumin on anxiety, depression, and cognitive functions using various behavioral tests.
- Results showed that LPS increased anxiety and depression while reducing learning and memory capabilities, but Adalimumab effectively mitigated these effects by reducing inflammation and regulating important biochemical markers related to cognitive function.
Background And Aim: Necrotizing Enterocolitis (NEC) is an inflammation-associated ischemic necrosis of the intestine. To investigate the effects of extra virgin olive oil (EVOO) on inflammation, oxidative stress, apoptosis, and histological changes in NEC-induced newborn rats.
Materials And Methods: 24 rats were randomly divided into three groups: control, NEC and NEC + EVOO.