Publications by authors named "H Enger"
Aim: Norway has a low prevalence of methicillin-resistant Staphylococcus aureus (MRSA) and reporting of all MRSA cases has been mandatory, including infections and carriage, since 1995 and 2005 accordingly. This provides a unique window to study the spread of MRSA in Norway over time. The aim of this study was to analyze the nationwide trends in the molecular epidemiology of MRSA in Norway over a period of 10 years.
View Article and Find Full Text PDFMultinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a framework for harmonisation of MRSA surveillance. The International Society of Antimicrobial Chemotherapy (ISAC) MRSA Working Group conducted a structured survey on MRSA surveillance programmes and organised a webinar to discuss the programmes' strengths and challenges as well as guidelines for harmonisation.
View Article and Find Full Text PDFA tale of two STs: molecular and clinical epidemiology of MRSA t304 in Norway 2008-2016.
Eur J Clin Microbiol Infect Dis
February 2022
The purpose of this study was to investigate the epidemiological, molecular, and clinical characteristics of MRSA t304/ST8 and t304/ST6 in Norway from 2008 to 2016. Clinical and epidemiological data were collected for each case included in the study. Strains were characterized by PCR, spa typing, antimicrobial susceptibility testing, and whole genome sequencing.
View Article and Find Full Text PDFArticle Synopsis
- MRSA is a reportable infection in Norway, Sweden, Denmark, Finland, and Iceland, with a notable increase in cases from 2009 to 2016 despite historically low prevalence.
- A comprehensive database was created to analyze new MRSA isolates, revealing a rise in incidence, particularly in Denmark, which reported the highest rate at 61.8 cases per 100,000 inhabitants.
- Significant genetic diversity was identified, with 2,344 different strains detected, and while some strains increased in prevalence across most countries, others displayed unique trends, suggesting both shared and country-specific MRSA characteristics.
Repeated introduction and spread of the MRSA clone t304/ST6 in northern Europe.
Clin Microbiol Infect
February 2021
Objectives: During the last decades several methicillin-resistant Staphylococcus aureus (MRSA) clones with the capability of global spread have emerged in the community. Here, we have investigated a large collection of clinical isolates belonging to MRSA clone t304/ST6, which has emerged in many European countries over the last years, in order to retrace its phylogeny and its spread.
Methods: We characterized 466 ST6 isolates from Denmark (n = 354), France (n = 10), Norway (n = 24), Sweden (n = 27) and the UK (n = 51).