Publications by authors named "H El Kabiri"

Background: Colorectal cancer (CRC), now the second most prevalent malignant tumor worldwide, is more prevalent in young adults. In recent decades, there has been progress in creating anti-colorectal cancer medications, including cytotoxic compounds.

Objectives: Novel anticancer drugs are needed to surmount existing obstacles.

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The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform for investigating the origin of cancer, paving the way for novel approaches to cancer treatment, drug testing, and tailored medical interventions.

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Article Synopsis
  • The study focused on developing and characterizing a new formulation of undecylenoyl phenylalanine (Sepiwhite) loaded into nanostructured lipid carriers (NLCs) aimed at reducing melanin production in the skin.
  • An optimized SEPI-NLC formulation showed promising results with a small particle size of 180.1 nm, high entrapment efficiency of 90.81%, and a stable shelf life of 9 months at room temperature.
  • The findings indicated that SEPI-NLCs had superior skin permeation and anti-tyrosinase activity compared to traditional formulations, indicating their potential effectiveness for treating hyperpigmentation.
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Nanoparticles (NPs) may help treat multidrug-resistant Staphylococcus aureus (MDR). This study prepared and evaluated chitosan/alginate-encapsulated Echinacea angustifolia extract against MDR strains. Evaluating synthesized NPs with SEM, DLS, and FT-IR.

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