Publications by authors named "H Ehrhardt"

Background: Retrograde trans-synaptic degeneration (TSD) following retro-chiasmal pathology, typically retro-geniculate in multiple sclerosis (MS), may manifest as homonymous hemi-macular atrophy (HHMA) of the ganglion cell/inner plexiform layer (GCIPL).

Objective: To determine the frequency, association with clinical outcomes, and retinal and radiological features of HHMA in people with MS (PwMS).

Methods: In this cross-sectional study, healthy controls (HC) and PwMS underwent retinal optical coherence tomography scanning.

View Article and Find Full Text PDF
Article Synopsis
  • - Cefiderocol is a new type of antibiotic designed to treat severe infections caused by multidrug-resistant bacteria, such as sepsis and certain types of pneumonia in adults.
  • - Its use in newborns is limited, with only a few documented cases so far.
  • - The text highlights a successful treatment case where cefiderocol was used to treat a newborn with pneumonia-related sepsis caused by the bacteria Stenotrophomonas maltophilia.
View Article and Find Full Text PDF

Phenotype distortion of lung resident mesenchymal stem cells (MSC) in preterm infants is a hallmark event in the pathogenesis of bronchopulmonary dysplasia (BPD). Here, we evaluated the impact of cyclic mechanical stretch (CMS) and hyperoxia (HOX). The negative action of HOX on proliferation and cell death was more pronounced at 80% than at 40%.

View Article and Find Full Text PDF
Article Synopsis
  • Population-based studies show conflicting data on preterm birth rates during the COVID-19 pandemic, highlighting a need for better understanding of birth characteristics.
  • This study compared perinatal care and very preterm birth rates before and during different phases of the COVID-19 pandemic in Hesse, Germany, using data from a quality assurance registry.
  • Findings indicated that very preterm birth rates decreased during the pandemic, especially during the second lockdown, with fewer births among mothers with serious health issues contributing to this decline.
View Article and Find Full Text PDF