Leptin concentrations during oral glucose tolerance test (OGTT) in obese and normal weight women.

Objective: To examine possible changes of leptin concentrations after the acute administration of glucose orally (OGTT).

Design: Seventy-five grams of glucose were administered per os in one group of obese and normal weight individuals and concentrations of glucose, insulin and leptin were measured at 0, 30, 60, 90 and 120 min. In an age matched control group of individuals with similar BMI water was given and leptin concentrations were measured before and after 30, 60, 90 and 120 min.