Publications by authors named "H E Moyses"
Article Synopsis
- - The study aimed to evaluate two host-response tests (TriVerity and MeMed BV) for accurately distinguishing between bacterial and viral acute respiratory infections (ARIs), addressing the issue of inappropriate antibiotic use.
- - 169 patients were tested; results showed that TriVerity had a Positive Percentage Agreement (PPA) of 81% while MeMed BV had a PPA of 96%, though both had limitations in accurately identifying non-bacterial infections.
- - The findings suggest both tests are similarly accurate for distinguishing bacterial infections, but further studies on their impact on antibiotic use and costs are needed to enhance clinical practices.
Background: A novel single-use, analyser-free, molecular point-of-care test for SARS-CoV-2 (Veros COVID-19 test, Sherlock Biosciences) could reduce time to results and improve patient care and flow in the emergency department (ED), but its performance in this setting is unknown.
Methods: Adults aged ≥18 years presenting to Southampton General Hospital (UK) with suspected COVID-19 were tested with the Veros COVID-19 test in addition to standard of care near-patient PCR. Measures of diagnostic accuracy were calculated for the Veros COVID-19 test stratified by Ct value.
Background: MecROX is a mechanistic sub-study of the UK-ROX trial which was designed to evaluate the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care. This is based on the scientific rationale that excess oxygen is harmful. Epithelial cell damage with alveolar surfactant deficiency is characteristic of hyperoxic acute lung injury.
View Article and Find Full Text PDFObjectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of eye movement desensitisation and reprocessing (EMDR), a psychological intervention programme, on symptoms related to traumatic stress in survivors of life-threatening medical events.
Secondary Objectives: to evaluate whether the effects of EMDR differ according to the nature of the medical event (associated diagnosis or setting), measured outcome (post-traumatic stress disorder (PTSD), anxiety, depression, or quality of life), or intervention (online, face-to-face, group or individual sessions).