The comprehensive relationship between combined anti-inflammatory and healthy diets and all-cause mortality in rheumatoid arthritis: results from NHANES 2003-2018.

Background: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disorder. Diet is recognized as a modifiable factor that may influence inflammation and potentially accelerate RA progression. Nevertheless, the effects of diverse dietary patterns and their combined impact on RA progression and long-term mortality remain inadequately understood.

Engineering the Self-Assembly Pathways of POSS-Peptide Amphiphiles to Form Diverse Cross-β Structures.

Cross-β structures are crucial in driving protein folding and aggregation. However, due to their strong aggregating tendency, the precise control of the self-assembly of β-sheet-forming peptides remains a challenge. We propose a molecular geometry strategy to study and control the self-assembly of cross-β structures.

Mechano-Graded Contact-Electrification Interfaces Based Artificial Mechanoreceptors for Robotic Adaptive Reception.

Triboelectrification-based artificial mechanoreceptors (TBAMs) is able to convert mechanical stimuli directly into electrical signals, realizing self-adaptive protection and human-machine interactions of robots. However, traditional contact-electrification interfaces are prone to reaching their deformation limits under large pressures, resulting in a relatively narrow linear range. In this work, we fabricated mechano-graded microstructures to modulate the strain behavior of contact-electrification interfaces, simultaneously endowing the TBAMs with a high sensitivity and a wide linear detection range.

A smartphone-based dual-modal lateral flow immunochromatographic assay for multiplex detection of illegal stimulant laxatives in slimming foods.

Stimulant laxatives (especially bisacodyl and sodium picosulfate) are frequently found to be adulterated into slimming foods, causing health-threatening effects to consumers. Sensitive, accurate, easy-to-operate and portable multiplex analytical techniques are still desired for the rapid screening of stimulant laxatives in slimming foods. In this work, a highly sensitive dual-modal colorimetric/photothermal lateral flow immunochromatographic assay (LFIA) was established based on facilely prepared concentrated gold nanoparticles (cAuNPs).

Influenza vaccine effectiveness against medically-attended influenza infection in 2023/24 season in Hangzhou, China.

From 2020, influenza viruses circulation was largely affected by the global coronavirus disease (COVID-19) pandemic, notably leading to the extinction of the B/Yamagata lineage and raising questions about the relevance of the quadrivalent influenza vaccine, which includes this lineage. Evaluating vaccine effectiveness (VE) against influenza infections is important to inform future vaccine programs. A test-negative case-control study was conducted in five tertiary hospitals in Hangzhou, the capital city of Zhejiang province, China, enrolling medically-attended patients aged >6 months who presented with influenza-like illness (ILI) from October 1, 2023, to March 31, 2024.