The Urban Heat Island Effect (UHIE) is a globally consistent pressure on biological species living in cities. Adaptation to the UHIE may be necessary for urban wild flora to persist in cities, but experimental evidence is scarce. Here, we report evidence of adaptive evolution in a perennial plant species in response to the UHIE.
View Article and Find Full Text PDFIntroduction: Heterozygous mutations in the progranulin gene (GRN) leading to decreased progranulin levels are one of the most frequent causes of inherited frontotemporal dementia (FTD). We evaluated progranulin levels in dried blood spots from capillary finger-stick collection (DBS).
Methods: Paired venous Ethylenediaminetetraacetic acid (EDTA) plasma and DBS samples were collected from each participant with or without pathogenic GRN mutations.
There is a critical need to generate age- and sex-specific survival curves to characterize chronological aging consistently across nonhuman primates (NHP) used in biomedical research. Sex-specific Kaplan-Meier survival curves were computed in 12 translational aging models: baboon, bonnet macaque, chimpanzee, common marmoset, coppery titi monkey, cotton-top tamarin, cynomolgus macaque, Japanese macaque, pigtail macaque, rhesus macaque, squirrel monkey, and vervet/African green. After employing strict inclusion criteria, primary results are based on 12,269 NHPs that survived to adulthood and died of natural/health-related causes.
View Article and Find Full Text PDFBoard certified behavior analysts (BCBAs) working in the schools often are charged with supporting students with and without disabilities who engage in challenging behavior. Meeting the unique needs of these students often requires a collaborative approach with other school-based professionals. We specifically sought to understand how behavior analysts engage in interprofessional collaboration with school psychologists (SPs), professionals who also have training to support students who engage in challenging behavior.
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