Publications by authors named "H E Gonzalez"

Neuromorphic computing is a brain-inspired approach to hardware and algorithm design that efficiently realizes artificial neural networks. Neuromorphic designers apply the principles of biointelligence discovered by neuroscientists to design efficient computational systems, often for applications with size, weight and power constraints. With this research field at a critical juncture, it is crucial to chart the course for the development of future large-scale neuromorphic systems.

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Serial macromolecular crystallography has become a powerful method to reveal room temperature structures of biological macromolecules and perform time-resolved studies. ID29, a flagship beamline of the ESRF 4th generation synchrotron, is the first synchrotron beamline in the world capable of delivering high brilliance microsecond X-ray pulses at high repetition rate for the structure determination of biological macromolecules at room temperature. The cardinal combination of microsecond exposure times, innovative beam characteristics and adaptable sample environment provides high quality complete data, even from an exceptionally small amount of crystalline material, enabling what we collectively term serial microsecond crystallography (SµX).

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Article Synopsis
  • Sleep disordered breathing (SDB) is a risk factor for stroke and Alzheimer’s disease, particularly among Hispanic/Latino adults, highlighting the need for research on its impact on brain health in this demographic.
  • This study, based on the Hispanic Community Health Study, analyzed the association between SDB and brain MRI measures in a diverse group of Hispanic/Latino adults, using data from 2,667 participants with neuroimaging conducted about 10 years after initial sleep assessments.
  • Results indicated that higher respiratory event index (REI) correlated with larger hippocampal volumes, while lower oxygen levels during sleep were related to expanded white matter hyperintensity (WMH) volumes, suggesting complex relationships between SDB, oxygen
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