Publications by authors named "H Duvekot"
Article Synopsis
- The study explores how glycemic variability (GV) affects pregnancy complications in women with type 1 diabetes during the pre- and periconception period, highlighting a gap in existing knowledge.
- Among 63 eligible women, 29 were included as their glucose data were analyzed through various metrics, revealing that a higher Average Daily Risk Range (ADRR) at conception correlated with greater complication scores.
- The findings suggest that the relationship between GV and complications varies based on the timing during pregnancy and the specific measurement metrics used.
European guidelines on perinatal care- Peripartum care Episiotomy.
J Matern Fetal Neonatal Med
December 2022
OF RECOMMENDATIONS1. Episiotomy should be performed by indication only, and not routinely (. Accepted indications for episiotomy are to shorten the second stage of labor when there is suspected fetal hypoxia ; to prevent obstetric anal sphincter injury in vaginal operative deliveries, or when obstetric sphincter injury occurred in previous deliveries (2.
View Article and Find Full Text PDFObjectives: Preeclampsia is associated with hypertension in later life, but the underlying pathophysiological mechanisms remain uncertain. We aimed to explore whether the angiogenic markers soluble Fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) measured in women with preeclampsia could be associated with hypertension 1 year after delivery.
Methods: This is a secondary analysis of a prospective cohort study, originally aimed to evaluate the use of sFlt-1/PlGF ratio to predict adverse outcome in women with (suspected) preeclampsia.
Article Synopsis
- Severe fetal growth restriction due to placental dysfunction is linked to high rates of perinatal death and health issues in newborns; sildenafil, a phosphodiesterase 5 inhibitor, may improve outcomes by enhancing blood flow in the placenta.
- A randomized clinical trial in the Netherlands studied whether sildenafil reduces perinatal mortality or severe morbidity in pregnant women with growth-restricted fetuses but was stopped early due to safety concerns, with no clear benefits identified.
- Out of 360 expected participants, 216 women were enrolled, with patients receiving either sildenafil or a placebo during the trial, aiming to assess the primary outcome of perinatal mortality or major neonatal issues until hospital discharge.