Introduction: Acute kidney injury (AKI) is one of the most frequent complications in septic shock cases, and has a high mortality rate. The aim of this study was to determine the value of urinary liver-type fatty acid binding protein (L-FABP) in early detection and outcome prediction of AKI in patients with sepsis and septic shock.
Methods: This prospective cohort study was conducted on patients who presented to the emergency department (ED) with sepsis or septic shock.
Unlabelled: Climate change, land development, and increased outdoor human activity have increased the prevalence and distribution of tick-borne pathogens, causing public health issues. Asia is a pivotal region of emerging infectious diseases caused by zoonotic disease. Therefore, this study aimed to construct effective surveillance systems and establish preventive strategies against novel tick-borne diseases.
View Article and Find Full Text PDFAvailable online A series of thirteen novel zerumbone oxime esters and five new azazerumbone derivatives were successfully synthesized. Most of these derivatives exhibited significant cytotoxic activity against four human tumor cell lines (HepG2, A549, HL-60, and AGS). Among them, three derivatives (3i, 3j, and 3k) demonstrated strong cytotoxic effects against all tested cell lines, with IC values ranging from 0.
View Article and Find Full Text PDFWith the growing emphasis on environmental protection, many coal mines in northern China were closed. However, the cessation of pumping operations in those closed mines has caused a rise in groundwater levels, giving rise to various safety and environmental concerns. Understanding the patterns of water level recovery is vital for effectively managing abandoned mine sites and ensuring the uninterrupted production of adjacent coal mines.
View Article and Find Full Text PDFBackground: Research on evaluating the efficacy of non-cultured epidermal cell suspension (NCECS) combined with excimer lamps for the treatment of vitiligo is currently unavailable. This research aims to evaluate the efficacy of this combination in treating vitiligo.
Methods: A prospective, controlled study was conducted from November 2021 to January 2024.