LOAD limits for ambulatory pulse pressure and double product in normotensive and hypertensive subjects.

Objective: The aim of this study was to to determine possible daytime (awake hours) and nighttime (sleeping hours) LOAD limits for ambulatory pulse pressure (PP) and double product (DP) in hypertensive (HT) subjects and secondly to assess whether there were significant differences in the LOAD values between hypertensive (HT) and normotensive (NT) subjects.

Methods: Seventy-eight untreated essential HT (46 female, 32 male; mean age 51.9+/-1.

Evaluation of DNA damage in lymphocytes of cardiologists exposed to radiation during cardiac catheterization by the COMET ASSAY.

This study was designed to evaluate the possible in vivo induction of DNA damage by exposure to radiation in cardiologists. The alkaline comet assay (single cell gel electrophoresis, SCGE), which appears to be a promising tool with which to estimate DNA damage at the single cell level, has been used. The assay was carried out on 30 cardiologists currently employed in a busy cardiac service and 30 healthy unexposed controls.

Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine.

Background: Hypertension is one of the most important causes of cardiovascular disease, and treatment of hypertension leads to a significant reduction in cardiovascular mortality and morbidity. Although calcium channel blockers are regarded as an important part of the therapeutic armamentarium against cardiovascular diseases, and are among the most frequently prescribed antihypertensive medications, concern has been aroused about these drugs, particularly the short-acting dihydropyrldine derivatives. However, the value of nifedipine GITS(Adalat-Crono), the long-acting dihydropyrldine, is in need of being re-established.

Early and late outcome of stenting in a consecutive series of patients with coronary lesions in vessels less than 2.8 mm in diameter.

In an attempt to determine the early and late outcomes of small vessel stenting, we retrospectively evaluated our database on 51 consecutive patients (41 males, mean age, 57.1 +/- 10.1 years) who underwent stenting of at least one significant lesion in a coronary artery with a reference vessel diameter (RVD) <2.

Head-to-head comparison of two different low-molecular-weight heparins in acute coronary syndrome: a single center experience.

Low-molecular-weight heparins (LMWH) of different types have yielded different results when used in the setting of unstable angina (UA) or non Q-wave myocardial infarction (NQMI). We compared the safety and therapeutic efficacy of two different LMWHs, namely dalteparin (Dalt.) and enoxaparin (Enox.