Publications by authors named "H Dhanalakshmi"
Background Objectives: Theileriosis is an important tick-bome hemoprotozoan disease of cattle which causes severe economic loss due to morbidity and mortality. A diagnostic test having high sensitivity, specificity and easy application at the field level is the need of the hour. In this regard Loop-mediated isothermal amplification (LAMP) is proven to be a sensitive, easy and time efficient method.
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- 6-Thioguanine encapsulated chitosan nanoparticles (6-TG-CNPs) were successfully created using an ionic-gelation method, resulting in spherical nanoparticles with a size around 261.63 nm and a notable entrapment efficiency of 44.27%.
- The release profile of these nanoparticles indicated a greater sustained drug release at a lower pH (4.8) compared to a neutral pH (7.4), with 91.40% release over 48 hours at pH 4.8.
- When tested on cancer cell lines (MCF-7 and PA-1), 6-TG-CNPs showed lower IC values (indicating higher potency) compared to
A five year old Holstein-Friesian cross breed cow was brought to Teaching Veterinary Clinical Complex with the history of anorexia, shivering and respiratory distress since a week. On close physical examination, enlarged prescapular lymph nodes and conjunctival mucous membranes with petechiae were noticed. Physiological parameters like rectal temperature, heart rate and respiratory rates were found to be 105.
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