CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3.

The vertebrate visual cycle hinges on enzymatically converting all--retinol (at-ROL) into 11--retinal (11c-RAL), the chromophore that binds to opsins in photoreceptors, forming light-responsive pigments. When struck by a photon, these pigments activate the phototransduction pathway and initiate the process of vision. The enzymatic isomerization of at-ROL, crucial for restoring the visual pigments and preparing them to receive new light stimuli, relies on various enzymes found in both the photoreceptors and retinal pigment epithelium cells.

Can the Urban Lifestyle Impact on Children BMI and Healthy Sleep?

Objectives: This study aimed to (i) compare children's lifestyle by urbanization level and (ii) examine the association between children's body mass index (BMI) and the risk of having unhealthy sleep (American Academy of Pediatrics).

Methods: Eight thousand one hundred fifty-nine children (4124 females) aged 6-9 years were observed and classified as urban or nonurban. Height and weight were measured, and the BMI was calculated.

Self-harm in the two years of greatest restrictions during the covid-19 pandemic: a cross-sectional study.

Objective: to analyze occurrence of self-harm, sociodemographic profile of victims and referrals in the first 24 months of the COVID-19 pandemic in São Paulo.

Method: cross-sectional study carried out by the Notifiable Diseases Information System with data on self-harm in São Paulo. The period outlined was March 2020 to February 2022.

Perceptions about children and adolescents' mental health crisis intervention: a qualitative systematic review.

This review aimed to identify and synthesize the perceptions of mental healthcare professionals, family members, and users about mental health crisis interventions for children and adolescents at hospitals and community mental health services. A qualitative systematic review was conducted following the Joanna Briggs Institution guidelines. The search was performed in 15 databases, with no temporal delimitation, and included studies in Portuguese, English, and Spanish.

Laser-Based Length-Measuring Board for the Measurement of Infant Body Length from Outside an Incubator: Proposal and Assessment of a Model.

Introduction: Opening the incubator side wall to insert a non-sterile length-measuring device carries the risk of microbial contamination and thermal instability for preterm infants. To reduce this inconvenience, a laser-based length-measuring board is proposed to measure body length from outside the incubator.

Methods: This device has two laser-line-shaped cursors which can be pointed to opposite ends of a segment to be measured.