Publications by authors named "H Dave"
Studies have reported that cellular metabolism at the tumor-immune microenvironment (TiME) serves as a critical checkpoint and perturbs/supports anti-cancer immunity. Extra cellular ATP (eATP) may mediate anti-cancer immune response; however, its catabolism by ectonucleotidase generates immunosuppressive adenosine. In the presented work, we have tried to repurpose doxycycline with or without an antagonist of ectonucleotidase for mitigating ATP metabolism and immunosuppression.
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- The study evaluates long-term outcomes for patients with tetralogy of Fallot, emphasizing the role of pulmonary annular hypoplasia and dysfunction over time.
- The research analyzed data from 131 heart repairs performed from 2004 to 2014, classifying patients based on the severity of their pulmonary annular conditions.
- Results showed a 100% survival rate, with varying rates of pulmonary valve replacement and right ventricular outflow tract reoperations among the different patient groups during the 9.6-year follow-up.
Injectable polymeric hydrogels delivered via endoscopic catheter have emerged as promising submucosal agents, offering durable, long-lasting cushions to enhance the efficacy of endoscopic submucosal dissection (ESD) for the removal of small, flat polyps from the gastrointestinal tract (GIT). However, polymer-based injections do not meet the easy-injectability criteria via catheter because their high viscosity tends to clog the catheter needle. To the best of knowledge, for the first time, report the fabrication of an amphiphile-based small molecule hydrogel of diglycerol monostearate (DGMS) that self-assembles to form hydrogel (DGMSH) for delivery via an endoscopic catheter.
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- A study analyzed data from 666 patients under 19 years old who underwent Holter monitoring after surgery, finding that while 70% had some arrhythmia, only 6% had severe cases.
- The research concluded that routine Holter monitoring may not be necessary for all pediatric patients post-surgery, as the chances of finding severe arrhythmias were low.