Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn's disease by bioinformatics analysis and machine learning.

Crohn's disease (CD) is a chronic inflammatory bowel disease with an unknown etiology. Ubiquitination plays a significant role in the pathogenesis of CD. This study aimed to explore the functional roles of ubiquitination-related genes in CD.

Boric acid-substituted phthalocyanine/ciprofloxacin co-assembled nanoparticles for constructing bacteria-responsive intelligent wound dressings with synergistic therapy and recognition of bacterial infections.

In contemporary times, the waning effectiveness of antibiotics against bacterial infections is progressively giving rise to significant concerns in public health. Although photodynamic technology possesses a potent ability to deactivate bacteria, its non-selective attack on normal cells poses potential side effects. Hence, in this study, a boric acid-substituted phthalocyanine photosensitizer (BAPc) was synthesized, exhibiting remarkable bacterial targeting capability.

Applications of modified lignocellulose and its composites prepared by different pretreatments in biomedicine: A review.

Lignocellulosic biomass represents one of the most abundant renewable biological resources on earth. Despite its current underutilization as a source of high-value chemicals, it has promising applications in biomedical and other fields. Presently, lignocellulose is predominantly transformed into high-value-added products, e.

Enhancing astaxanthin production from Chromochloris zofingiensis via blue light and exogenous inducers in plate photobioreactors.

This study investigates the photoinduction techniques for the maximization of astaxanthin production in Chromochloris zofingiensis following heterotrophic growth. Leveraging blue light, this study enhanced carbon allocation by suppressing the tricarboxylic acid cycle and activating the methylerythritol phosphate and pentose phosphate pathways to facilitate astaxanthin accumulation. Under blue light, an astaxanthin content of 5.