Publications by authors named "H D Steele"

This study investigated the influence of parents' Adult Attachment Interview (AAI) responses prior to the birth of a first child, on self-reported mental health symptoms of the first-born child in mid-adolescence. The sample comprised 51 first-born children aged 16 years, their mothers and fathers from a low-risk community urban sample, White, British and 70% middle class. Mothers' responses to the AAI were the strongest predictor of their adolescent children's self-reported mental health symptoms.

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With the rising demand for sustainable renewable resources, microorganisms capable of producing bioproducts such as bioplastics are attractive. While many bioproduction systems are well-studied in model organisms, investigating non-model organisms is essential to expand the field and utilize metabolically versatile strains. This investigation centers on TIE-1, a purple non-sulfur bacterium capable of producing bioplastics.

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Article Synopsis
  • Phosphonate and phosphate prodrugs are important for improving drug absorption, but their toxic metabolites pose risks that must be addressed.
  • The study specifically looks at how certain metabolite compounds affect pancreatic cancer cells, glioblastoma cells, and mouse astrocytes, finding that 2-naphthol is particularly toxic to these cell types.
  • A clear trend shows that normal cells are generally more vulnerable to the toxic effects of these prodrug metabolites compared to cancer cells, highlighting the need to consider this toxicity during drug development.
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Background: Attachment theory has served as an influential framework for understanding psychopathology, partly due to reliable assessment methodology. The influence of insecure attachment on attitudes toward the body and the impact this might have for the development of psychopathology is however less well elucidated.

Method: A total of 123 adolescents (35 with borderline personality disorder or BPD, 25 with other personality disorders [OPD] and 63 comprising a normative control group) were interviewed with the Adult Attachment Interview (AAI) and the Mirror Interview (MI).

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