A revision to marble burying: video analysis during the marble burying task is imperative to understanding rodent behavior.

The translational value of the marble burying task (MBT) is debatable. Here we performed video analysis of behaviors during the MBT to accurately capture the details of all behaviors displayed during this task. Our results show that a count of marbles buried at the end of the task may not be a good translational correlate of the 'intentional marble burying' that the task is assumed to measure.

Gonadal hormones impart male-biased behavioral vulnerabilities to immune activation via microglial mitochondrial function.

There is a strong male bias in the prevalence of many neurodevelopmental disorders such as autism spectrum disorder. However, the mechanisms underlying this sex bias remain elusive. Infection during the perinatal period is associated with an increased risk of neurodevelopmental disorder development.

Developing a training programme for midwives and maternity support workers facilitating a novel intervention to support women with anxiety in pregnancy.

Background: The RAPID-2 intervention has been developed to support women with symptoms of mild-to-moderate anxiety in pregnancy. The intervention consists of supportive discussions with midwives, facilitated discussion groups and access to self-management materials. This paper reports the development of a training programme to prepare midwives and maternity support workers to facilitate the intervention.

Microbial responses are unreliable indicators of copper ecotoxicity in soils contaminated by mining activities.

Metal contamination of soil has become a serious environmental problem worldwide. Many studies have attempted to infer metal ecotoxicity from soil microbial responses. However, much of the data from these studies tends to be inconsistent and difficult to interpret.

Transcatheter aortic valve implantation for degenerated aortic valves: Experience with a new supra-annular device. The Spanish Allegra valve-in-valve (SAVIV) registry.

Objectives: The objective was to evaluate the results of valve-in-valve procedures performed with the Allegra device.

Background: Transcatheter aortic valve implantation to treat degenerated biological aortic valves (valve-in-valve) is an established procedure in most catheterization laboratories, but the results are poorer than procedures done in native aortic stenosis. The Allegra device (Biosensors, Morges, Switzerland) has an excellent design to treat these patients.