Publications by authors named "H D Khanna"

Objective: To identify chest X-ray (CXR) characteristic of Pediatric pulmonary drug-resistant tuberculosis (DRTB) in comparison to drug sensitive tuberculosis (DSTB) for early identification and treatment of DRTB.

Methods: This was a prospective cross-sectional study in which CXR patterns of DS and DR patients aged 1 month to 18 years were categorized into different variants including pleural effusion, cavity lesion, hilar or mediastinal lymph node (LN), consolidation, pneumothorax, pericardial effusion, miliary TB, nodular shadow, and collapse. The consensus between the pulmonary physician and radiologist was measured using weighted kappa test.

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Article Synopsis
  • Child development assessment tests are crucial for educational placement and identifying cognitive weaknesses, but most research has been limited to high-income countries, making adaptation to other contexts challenging.
  • As part of a study on the impact of childhood vaccines in rural Haryana, India, researchers aimed to assess the feasibility of enrolling local children and conducting development assessments for kids aged 18 months to 8 years.
  • A rigorous seven-step adaptation process was developed to culturally and contextually tailor three assessment tests, which included translation, back-translation, iterative adaptation, and field-testing to ensure validity and relevance in the rural setting.
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Background: We previously demonstrated that deep brain stimulation (DBS) of lateral cerebellar nucleus (LCN) can enhance motor recovery and functional reorganization of perilesional cortex in rodent models of stroke or TBI.

Objective: Considering the treatment-related neuroplasticity observed at the perilesional cortex, we hypothesize that chronic LCN DBS-enhanced motor recovery observed will carry-over even after DBS has been deactivated.

Methods: Here, we directly tested the enduring effects of LCN DBS in male Long Evans rats that underwent controlled cortical impact (CCI) injury targeting sensorimotor cortex opposite their dominant forepaw followed by unilateral implantation of a macroelectrode into the LCN opposite the lesion.

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Cell-mediated immune response is critical for () control. Understanding of pathophysiology and role played by different cell mediators is essential for vaccine development and better management of patients with . A complex array of cytokines and chemokines are involved in the immune response against ; however, their relative contribution in protection remains to be further explored.

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Background: Diabetic patients are at higher risk of cardiovascular morbidity and mortality. NT-proBNP levels measurements are useful for the assessment of risk in heart failure patients in emergency condition and give the faster result. Further, it also offers lower cost and unnecessary hospitalization and follow-up cost.

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