Publications by authors named "H D Karsten"
Dairy production is a key agricultural enterprise in the Upper Chesapeake Bay (UCB) basin, where phosphorous (P) and nitrogen (N) loading contribute to eutrophication. Import of forages and grains and application of mineral fertilizers contribute to nutrient imbalances in the basin. The UCB Long-Term Agroecosystem Research Cropland Common Experiment aims to evaluate diverse crop rotations that minimize the need for imported feed, maximize year-round living cover, and reduce nutrient losses.
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- Engineering immune cells, particularly CAR-T-cell therapies, has advanced significantly in treating hematological malignancies like acute lymphoblastic leukemia (B-ALL) and multiple myeloma, improving outcomes for patients with previously poor prognoses.
- This review covers current research and innovations in CAR-T-cell therapy for various blood cancers, highlighting strategies applied across different diseases and identifying both common and unique treatment challenges.
- It also discusses the limitations of CAR-T-cell therapy, including issues with the tumor microenvironment and adverse effects, and hints at future advancements such as artificial intelligence in CAR-T-cell engineering.
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- The study investigates the T-cell responses specific to NSP12 protein in COVID-19 patients and compares them to those in uninfected individuals and pre-pandemic controls.
- It finds that both COVID-19 patients and seronegative controls exhibit similar breadth of T-cell responses to NSP12 peptides, but COVID-19 patients have a higher magnitude of response.
- The presence of cross-reactive T-cell responses from common cold coronaviruses suggests pre-existing immunity, while also highlighting the complex nature and incomplete understanding of T-cell responses to SARS-CoV-2.
Background: Currently, the development of the incidence of acute kidney injury (AKI) and the influence of age and gender on the condition in Germany is unclear.
Materials And Methods: Data were extracted from the national database of Federal Health Reporting. It was then normalized for demographic changes.
Background: Therapy satisfaction is widely considered an important aspect of clinical care. Still, there are currently no freely available questionnaires for its measurement. We developed the Lübeck Medication Satisfaction Questionnaire (LMSQ) for that purpose.
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