Publications by authors named "H D Hoffmann"

The brain-age gap, i.e. the difference between the brain age estimated from structural MRI data and the chronological age of an individual, has been proposed as a summary measure of brain integrity in neurodegenerative diseases.

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Article Synopsis
  • The study surveyed pathologists and thoracic surgeons from the IASLC to evaluate their views on the R classification for lung cancer, with a response rate of 72% from 447 professionals.
  • Findings revealed geographic differences in R classification usage, with Europe and Asia often reporting R status, while 70% of North American pathologists rarely do, and varied practices regarding who assigns R categories between regions.
  • The "uncertain resection" category (R(un)) is largely unused globally, highlighting the need for more evidence and standardization in reporting surgical margins and R categories in pathology.
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Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The rapid development of highly effective vaccines against SARS-CoV-2 has altered the trajectory of the pandemic, and antiviral therapeutics have further reduced the number of COVID-19 hospitalizations and deaths. Coronaviruses are enveloped, positive-sense, single-stranded RNA viruses that encode various structural and non-structural proteins, including those critical for viral RNA replication and evasion from innate immunity.

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Management of labor in women with diabetes is challenging due to the high risk of peri- and postpartum complications. To avoid cesarean section and assist with labor progression, Pitocin, a synthetic oxytocin, is frequently used to induce and augment labor. However, the efficacy of Pitocin is often compromised in diabetic pregnancies, leading to increased cesarian delivery.

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