Publications by authors named "H D Bear"

Article Synopsis
  • Researchers wanted to find better ways to help young people avoid mental health problems, especially depression.
  • They tested three different apps: one that helps build emotional skills, one based on cognitive behavioral therapy (CBT), and one for keeping track of feelings.
  • The study included 1,262 young people from several countries, and they checked how the apps helped reduce depression symptoms after three months.
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Article Synopsis
  • The study investigates the effectiveness of three different self-help apps aimed at improving mental wellbeing among young people, specifically comparing a personalised emotional competence app, a cognitive behavioural therapy (CBT) app, and a self-monitoring app.
  • Conducted as a randomised controlled trial across four countries, the research involved 2532 young participants aged 16-22 without major depression, who were monitored for 12 months to assess changes in mental wellbeing.
  • The primary measurement for evaluating success was the Warwick-Edinburgh Mental Well Being Scale (WEMWBS) at a 3-month follow-up, ensuring that the outcomes were objectively assessed by unaware evaluators.
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Background: NRG Oncology NSABP B-39/RTOG 0413 compared whole-breast irradiation (WBI) to accelerated partial-breast irradiation (APBI). APBI was not equivalent to WBI in local tumor control. Secondary outcome was quality of life (QOL).

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Background: Smartphone apps may provide an opportunity to deliver mental health resources and interventions in a scalable and cost-effective manner. However, young people from marginalized and underserved groups face numerous and unique challenges to accessing, engaging with, and benefiting from these apps.

Objective: This study aims to better understand the acceptability (ie, perceived usefulness and satisfaction with an app) and feasibility (ie, the extent to which an app was successfully used) of mental health apps for underserved young people.

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Background: The PENELOPE-B study demonstrated that the addition of 1-year post-neoadjuvant palbociclib to endocrine therapy (ET) in patients with high-risk early breast cancer (BC) did not improve invasive disease-free survival (iDFS) compared to placebo. Here, we report results for premenopausal women.

Patients And Methods: Patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative BC at high risk of relapse [defined as no pathological complete response after neoadjuvant chemotherapy and a clinical, pathological stage, estrogen receptor, grading (CPS-EG) score ≥3 or 2/ypN+] were randomized to receive 13 cycles of palbociclib or placebo + standard ET.

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