Transperineal permanent seed implantation of "low-risk" prostate cancer: 5-year-experiences in 118 patients.

Purpose: To evaluate 5-year prostate-specific antigen (PSA) relapse-free survival of transperineal permanent seed implantation (TPSI) in 118 patients with "low-risk" prostate cancer, that means stage cT1c-T2a, Gleason Score < 7, and initial PSA value < 10 ng/ml.

Patients And Methods: From 04/1999 to 06/2002, a total of 118 patients underwent a mono-TPSI, using ultrasound-based preplanning and intraoperative verification by both ultrasound and conventional fluoroscopy as well as postoperative CT planning. Patients were monitored during the 1st year in 3-month intervals, and in 6-monthly intervals from then onward.

Quality assurance in stereotactic radiosurgery/radiotherapy according to DIN 6875-1.

The new DIN ('Deutsche Industrie-Norm') 6875-1, which is currently being finalised, deals with quality assurance (QA) criteria and tests methods for linear accelerator and Gamma Knife stereotactic radiosurgery/radiotherapy including treatment planning, stereotactic frame and stereotactic imaging and a system test to check the whole chain of uncertainties. Our existing QA program, based on dedicated phantoms and test procedures, has been refined to fulfill the demands of this new DIN. The radiological and mechanical isocentre corresponded within 0.

[Quality assurance in stereotactic space. Determination of the accuracy of aim and dose in single dose radiosurgery].

Background: Single dose irradiation techniques require methods of quality assurance of high precision. The complete operational sequence of a treatment from imaging over irradiation planning up to the patient irradiation has to be controlled and verified in a phantom (Figure 2). These demands receive special topicality by the E-DIN 6875-1 [38], which will appear soon.