Publications by authors named "H Cobb"

University core curricula and accreditation standards for healthcare profession programs can be challenging to align. Additionally, interprofessional education (IPE) requirements for healthcare professions curricula have been designed to prepare learners for future practice. This paper describes alignment of an introductory IPE course with embedded Interprofessional Education Collaborative core competencies to specific university Core Curriculum attributes.

View Article and Find Full Text PDF

Keener et al. (2023) raise concerns about the trustworthiness of Industrial/Organizational (IO) Psychology research and related fields due to the low reproducibility and replicability of research findings. The authors provide various solutions to resolve this crisis, such as improving training, realigning incentives, and adopting open science practices.

View Article and Find Full Text PDF

Transplantation of stem cell-derived retinal pigment epithelium (RPE) cells is a promising potential therapy for currently incurable retinal degenerative diseases like advanced dry age-related macular degeneration. In this study, we designed a set of clinically applicable devices for subretinal implantation of RPE grafts, towards the overarching goal of establishing enabling technologies for cell-based therapeutic approaches to regenerate RPE cells. This RPE transplant kit includes a custom-designed trephine for the production of RPE transplants, a carrier for storage and transportation, and a surgical device for subretinal delivery of RPE transplants.

View Article and Find Full Text PDF

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. Drusen are key contributors to the etiology of AMD and the ability to modulate drusen biogenesis could lead to therapeutic strategies to slow or halt AMD progression. The mechanisms underlying drusen biogenesis, however, remain mostly unknown.

View Article and Find Full Text PDF
Article Synopsis
  • There is an urgent need to create a GMP-compliant protocol for producing three-dimensional retinal organoids.
  • This protocol is essential for advancing the transplantation of retinal tissue and cells derived from human induced pluripotent stem cells (hiPSCs) to clinical trials.
  • The ultimate goal is to provide effective patient treatment for retinal degenerative diseases.
View Article and Find Full Text PDF