Reconstruction of anterior talofibular ligament and posterior tibiotalar ligament enhance ankle stability after total talus replacement by finite element analysis.

Total talus replacement has been demonstrated to increase ankle instability. However, no studies have explored how to enhance postoperative stability. This study aims to explore the effect of collateral ligament reconstruction on ankle stability by finite element analysis.

Evaluating Efficacy and Safety of Crisaborole in Managing Childhood Mild to Moderate Atopic Dermatitis: A Systematic Review and Meta-Analysis.

Atopic dermatitis (AD) is a common chronic inflammatory skin disorder globally. Crisaborole, a nonsteroidal topical phosphodiesterase 4 inhibitor (PDE4i), has been utilized in treating AD. Crisaborole regulates the production of inflammatory cytokines, which are usually overactive among AD patients.

An exploratory study of pilot EEG features during the climb and descent phases of flight.

Objectives: The actions and decisions of pilots are directly related to aviation safety. Therefore, understanding the neurological and cognitive processes of pilots during flight is essential. This study aims to investigate the EEG signals of pilots to understand the characteristic changes during the climb and descent stages of flight.

A genomic variation map provides insights into potato evolution and key agronomic traits.

Hybrid potato breeding based on diploid inbred lines is transforming the way of genetic improvement of this staple food crop, which requires a deep understanding of potato domestication and differentiation. Here, we resequenced 314 diploid wild and landrace accessions to generate a variome map of 47,203,407 variants. Using the variome map, we discovered the reshaping of tuber transcriptome during potato domestication, characterized genome-wide differentiation between landrace groups Stenotomum and Phureja, and identified a jasmonic acid biosynthetic gene possibly affecting tuber dormancy period.

A Survey of Wild Indigenous Orchid Populations in Western Australia Reveals Spillover of Exotic Viruses.

is a terrestrial orchid endemic to southwestern Australia. The virus status of has not been studied. Eighty-three samples from 16 populations were collected, and sequencing was used to identify RNA viruses from them.