Incidence and mortality by cancer in the Pasto municipality, Colombia. 2013-2017.

Introduction: The information permanently produced by population cancer registries is the input used by decision makers of the local and national health systems in order for planning cancer prevention strategies and evaluating the impact of their interventions.

Objective: To determine the incidence and mortality from cancer in the municipality of Pasto Colombia, 2013-2017 period.

Methods: Descriptive observational study of cancer morbidity and mortality.

Targeted muscle effort distribution with exercise robots: Trajectory and resistance effects.

The objective of this work is to relate muscle effort distributions to the trajectory and resistance settings of a robotic exercise and rehabilitation machine. Muscular effort distribution, representing the participation of each muscle in the training activity, was measured with electromyography sensors (EMG) and defined as the individual activation divided by the total muscle group activation. A four degrees-of-freedom robot and its impedance control system are used to create advanced exercise protocols whereby the user is asked to follow a path against the machine's neutral path and resistance.

Real-time optimization of an ellipsoidal trajectory orientation using muscle effort with Extremum Seeking Control.

We present an approach for real-time model-free optimization of the orientation of the elliptical trajectory. The performance is evaluated in simulation and experimental stages. Our model-free approach is based on the use of Extremum Seeking Control (ESC) as the real-time optimizer.

Improving circulating tumor cells enumeration and characterization to predict outcome in first line chemotherapy mCRPC patients.

Introduction: There is a critical need of new surrogate markers for improving the therapeutic selection and monitoring of metastatic prostate cancer patients. Nowadays clinical management of these patients is been driven by biochemical and clinical parameters without enough accuracy to allow a real personalized medicine. The present study was conducted to go insight the molecular profile of circulating tumor cells (CTCs) isolated from advanced metastatic castration-resistant prostate cancer (mCRPC) with the aim of identifying prognostic marker with potential utility for therapy selection and monitoring.