Preparation and radon exhalation characteristics of fracture granite similar materials in Beishan underground research laboratory.

The mechanism of radon exhalation from surrounding rock fracture has important guiding significance for radon prevention and control in underground research laboratories. The optimal ratio scheme of similar materials in the granite surrounding rock of Beishan underground laboratory was obtained by orthogonal test. The radon exhalation characteristics of fractured rock samples under dry and saturated conditions were obtained by using 10 standard joint roughness coefficient (JRC) curves.

Silencing of APEX1 triggers ferroptosis in clear cell renal cell carcinoma via APP-mediated activation of p53/xCT signaling.

Background: Apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1) is involved in regulating the proliferation, invasion, migration, and other malignant progression of various cancer cells. However, its mechanism in clear cell renal cell carcinoma (ccRCC) remains unclear.

Methods: UALCAN database was performed to predict APEX1 expression in ccRCC.

Identification and monitoring of cell heterogeneity from plasmid recombination during limonene production.

Detecting alterations in plasmid structures is often performed using conventional molecular biology. However, these methods are laborious and time-consuming for studying the conditions inducing these mutations, which prevent real-time access to cell heterogeneity during bioproduction. In this work, we propose combining both flow cytometry and fluorescence-activated cell sorting, integrated with mechanistic modelling to study conditions that lead to plasmid recombination using a limonene-producing microbial system as a case study.

Autoimmune Diseases and Molecular Mimicry in Tuberculosis.

Unlabelled: Comorbidities in tuberculosis patients are increasing annually. Autoimmune pathology may influence the diagnosis and treatment of tuberculosis (TB). However, the molecular mimicry between (Mtb) and human autoantigens is an important provocative factor in the development of autoimmunity on one hand.

Optimizing tobacco quality and yield through the scientific application of organic-inorganic fertilizer in China: a meta-analysis.

China is the largest producer and consumer of tobacco ( L.) in the world, and the cultivation and production of tobacco have extremely high economic value and social influence. Applying organic-inorganic fertilizer is a key strategy for boosting tobacco yield and quality.