Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress.

Diisooctyl phthalate (DIOP), a common phthalate plasticizer, is frequently encountered in everyday life. Despite its widespread use, there is a dearth of toxicological research on DIOP, resulting in incomplete knowledge of its potential harmful effects. Our current research endeavored to provide a comprehensive evaluation of DIOP's toxicological profile using both cellular and Caenorhabditis elegans models as our in vitro and in vivo study subjects.

Improving Optical Efficiency and Luminance of GaN-Based Micro-Light-Emitting Diodes for High-Resolution Displays via NH Plasma Pretreatment.

GaN-based micro-light-emitting diodes (Micro-LEDs) are regarded as promising light sources for near-eye-display applications such as augmented reality/virtual reality (AR/VR) displays due to their high resolution, high brightness, and low power consumption. However, the application of Micro-LEDs in high-pixel-per-inch (PPI) displays is constrained by the drop in efficiency caused by sidewall defects in small-sized devices. In this study, a process method involving NH plasma pretreatment to reduce sidewall defects is proposed and investigated for enhancing the external quantum efficiency (EQE) of small-sized devices.

Biosynthetic graft versus autologous graft tympanoplasty: a prospective randomized controlled trial.

Purpose: The aim of this study was to compare the graft success rate, hearing outcome, and operative time in patients undergoing tympanoplasty for tympanic membrane perforation with the use of either biosynthetic or autologous graft material.

Methods: This was a prospective randomized controlled trial performed at a regional hospital. 41 patients were enrolled and randomized, with 20 patients allocated to the treatment arm (biosynthetic graft) and 21 patients allocated to the control arm (autologous graft).

ZIKV prM hijacks PIM1 kinase for phosphorylation to prevent ubiquitin-mediated degradation and facilitate viral replication.

Introduction: Viral infection usually stimulates a variety of host cell factors to modulate the life cycle of the virus. PIM1, a serine/threonine protein kinase widely involved in cell proliferation, survival, differentiation and apoptosis, was recently reported to be upregulated by Zika virus (ZIKV) infection. However, how ZIKV-PIM1 interactions affect the viral life cycle are not fully understood.