Publications by authors named "H C Hempel"

Article Synopsis
  • * Combining two phosphonic acid compounds, Me-4PACz and another PA with different functional groups, enhances film formation, improves charge transport, and reduces energy losses at the interface.
  • * Achieving a high current density of 40.2 mA/cm and greater than 30% power conversion efficiency, this research showcases the potential for creating highly efficient and industry-compatible tandem solar cells.
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  • The study evaluated the reproducibility of enzyme-linked immunosorbent assays (ELISAs) that measure various anti-HPV immunoglobulin isotypes (IgG1, IgG3, IgA, and IgM) in serum samples from participants vaccinated with the bivalent HPV vaccine.
  • Results showed low levels of IgG2 and IgG4, with varying coefficients of variation (CVs) indicating differences in reproducibility across technicians and days; IgM had higher CVs compared to the other isotypes.
  • The findings confirmed that the ELISAs are reliable for detecting HPV16 antibodies, with all isotype antibodies showing high intraclass correlation coefficients (ICCs) and significant correlations between
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: The primary endothelial NADPH oxidase isoform 4 (NOX4) is notably induced during hypoxia, with emerging evidence suggesting its vasoprotective role through HO production. Therefore, we aimed to elucidate NOX4's significance in endothelial function under hypoxia. : Human vessels, in addition to murine vessels from mice, were explored.

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The COVID-19 pandemic led to the rapid development of tests to diagnose SARS-CoV-2 infection and ascertain the prevalence of infection, along with the formulation of various treatments and vaccines. Globally, over 220 anti-SARS-CoV-2 serological assays have been developed for laboratory use, and many of these assays are currently used to assess immune responses against SARS-CoV-2. However, because these assays were independently developed by different manufacturers with different target antigens, immunoglobulin detection, technologies, and data reporting approaches, the results are not directly comparable, making it challenging to draw conclusions regarding immune responses at the population level.

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Article Synopsis
  • This study investigates inconsistencies between various measures of blood sugar, particularly HbA1c, fructosamine, and continuous glucose monitoring (CGM) in managing diabetes in primary care.
  • Over a period of about 90 days, they assessed these measures in adults with prediabetes or type 2 diabetes, finding a significant mismatch in results, particularly with HbA1c compared to fructosamine and CGM.
  • The findings suggest that relying solely on HbA1c can lead to misleading diabetes management decisions, emphasizing the need to consider multiple measures for a more accurate clinical assessment.
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