Publications by authors named "H C Heitkamp"

Article Synopsis
  • Myofascial trigger point therapy (MTrP) is used for pain relief, but its mechanisms, including central pain modulation (CPM), are not fully understood; this study explores their potential correlation in healthy individuals.
  • The study involved 94 participants subjected to heat and pressure stimuli to assess pain responses before and after MTrP and CPM interventions, systematically measuring mild and intense pressure on specific areas.
  • Results indicated a significant correlation between the pain relief from MTrP and CPM, suggesting overlapping mechanisms; the relationship was stronger with more intense stimulation.
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Background And Objective: Recently, a consensus process specified a core outcome set (COS) of domains to be assessed in each comparative effectiveness research and clinical practice related to acute postoperative pain. Physical function (PF) was one of these domains. The aim of this review was to investigate which patient-reported outcome measures (PROMs) are used to assess PF after total knee arthroplasty (TKA) in clinical trials and if they fulfil basic requirements for a COS of PROMs based on their psychometric properties.

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Background: Myokines discharged from working muscles are intensively researched in view of rising importance of preventive and secondary preventive effects of the autocrine, paracrine and endocrine functions.

Objectives: Recording of the current state of knowledge on the paracrine and endocrine effects of myokines and evaluation of training measures to optimize myokine concentration.

Method: A selective database-driven literature search was carried out on myostatin, interleukin-6 (IL-6), interleukin-15 (IL-15), irisin, cathepsin B, brain-derived neurotrophic factor (BDNF), meteorin-like and kynurenine for the period 2011 until June 2021.

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Background: New European and American guidelines for nutrition in hypercholesterolemia coincided with a lowered target value for LDL(Low density lipoprotein)-cholesterol.

Methods: Guidelines, their development and supporting meta-analyses were searched in Medline/PubMed and Cochrane database and analyzed for the influence of fat, carbohydrates and protein on reduction of LDL-cholesterol as well as the differences between European and American guidelines.

Results: In contrast to European guidelines, American guidelines increasingly refrain from controlling fat in nutrition, based on studies on the influence of nutrition on LDL-cholesterol and saturated fat; instead, monosaccharides and disaccharides are to be reduced from 15% to 10% of total calories for avoidance of high LDL-cholesterol and a non-alcoholic fatty liver.

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In endurance running, where fluid and nutritional support is not always readily available, the carriage of water and nutrition is essential. To compare the economy and physiological demands of different carriage systems, 12 recreational runners (mean age 22.8 ± 2.

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