Publications by authors named "H C Cunningham-Hollinger"

Article Synopsis
  • Mastitis impacts the economy and welfare of sheep affected by both clinical and subclinical forms, prompting research on microbial diversity in milk from healthy ewes.
  • The study sequenced the V4 region of the 16S rRNA gene from milk collected at various postpartum stages from ewes fed different zinc diets during gestation and lactation.
  • Findings revealed diverse microbial communities with notable mastitis-related pathogens present, while the effects of breed, dietary zinc, and somatic cell counts on milk microbiome diversity varied, particularly during early lactation.
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The jejunum is a critical site for nutrient digestion and absorption, and variation in its ability to take up nutrients within the jejunum is likely to affect feed efficiency. The purpose of this study was to determine differences in gene expression in the jejunum of beef steers divergent for residual feed intake (RFI) in one cohort of steers (Year 1), and to validate those genes in animals from a second study (Year 2). Steers from Year 1 ( = 16) were selected for high and low RFI.

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Optimization of host performance in cattle may be achieved through programming of the rumen microbiome. Thus, understanding maternal influences on the development of the calf rumen microbiome is critical. We hypothesized that there exists a shared microbial profile between the cow and calf rumen microbiomes from birth through weaning.

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In cattle, the rumen is an important site for the absorption of feed by-products released by bacterial fermentation, and variation in ruminal function plays a role in cattle feed efficiency. Studies evaluating gene expression in the rumen tissue have been performed prior to this. However, validating the expression of genes identified in additional cattle populations has been challenging.

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Subclinical mastitis is a common intramammary disease in sheep production systems. Expenses associated with compromised animal performance, therapeutic interventions, and decreased ewe longevity make efforts to minimize its prevalence worthwhile. The objectives of this study were to 1) quantify the prevalence of subclinical mastitis throughout lactation, 2) evaluate the impact of bedding treatments on subclinical mastitis during early lactation, 3) evaluate the efficacy of prophylaxis and feed restriction during weaning on subclinical mastitis cure rates, and 4) identify levels and types of antimicrobial resistance in milk-derived bacteria.

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