Purpose: To clarify the effects of preoperative nutritional evaluation on the prognosis of patients with tongue squamous cell carcinoma.
Methods: This retrospective cohort study involves 126 consecutive patients who underwent radical surgery as their initial treatment and received treatment for >3 years. The markers considered in this study are GGT (γ-GTP), CAR (C-reactive protein (CRP)-to-Alb Ratio), GLR (GGT-to-Lymphocytes Ratio), GPR (GGT-to-Platelet ratio), GNR (GGT-to-Neutrophil ratio), NLR (Neutrophil-to-Lymphocyte ratio), PLR (platelet-to-lymphocytes ratio), OPNI (Onodera`s prognostic nutritional index), PINI (Prognostic Immune and Nutritional Index) and Albumin (Alb).
Indian J Otolaryngol Head Neck Surg
December 2024
This study reports a rare case of a dentigerous cyst in a malformed tooth in the mandible of a 5-year-old Japanese boy. Panoramic radiography revealed a cystic lesion with hard tissues inside. The patient underwent surgery under general anesthesia.
View Article and Find Full Text PDFThis report presents a rare case of direct invasion from a metastatic submandibular lymph node (SMLN) to submandibular gland (SMG) in a resected specimen of neck dissection (ND) of buccal mucosal squamous cell carcinoma (SCC). The patient was an 82-year-old woman with a clinical diagnosis of the left buccal mucosal SCC (cT4bN2bM0, Stage IVB). The tracheostomy, modified radical neck dissection, buccal mucosal cancer resection including maxillary partial resection, mandibular segmentectomy, and reconstructive surgery with a plate and a free rectus abdominis flap were performed.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
September 2024
Background: Locoregional surgical pathology, with surgical margins at the primary site and lymph node (LN) metastasis, particularly extranodal extension (ENE), plays an important role in the prognosis of oral squamous cell carcinoma (OSCC). In addition, systemic inflammatory response and nutritional status are associated with poor prognosis.
Purpose: This study aimed to comprehensively assess the effect of inflammatory markers and locoregional factors on the prognosis of patients with OSCC who underwent neck dissection (ND).
Techniques for triggering neural differentiation of embryonic and induced pluripotent stem cells into neural stem cells and neurons have been established. However, neural induction of mesenchymal stem cells, including dental pulp stem cells (DPSCs), has been assessed primarily based on neural-related gene regulation, and detailed studies into the characteristics and differentiation status of cells are lacking. Therefore, this study was aimed at evaluating the cellular components and differentiation pathways of neural lineage cells obtained via neural induction of human DPSCs.
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