Publications by authors named "H Briemberg"
Article Synopsis
- This study explored how brain degeneration correlates with the progression of amyotrophic lateral sclerosis (ALS) by analyzing brain scans of 149 ALS patients and 144 healthy controls.
- Researchers used a texture analysis method on MRI scans to identify "autocorrelation," a biomarker indicating brain degeneration, focusing on different stages of the disease.
- Results showed that brain changes varied significantly depending on the criteria used for patient classification, suggesting that standard clinical trial measures may not fully capture the extent of brain degeneration in ALS patients.
Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder characterized by motor neuron degeneration. Significant research has begun to establish brain magnetic resonance imaging (MRI) as a potential biomarker to diagnose and monitor the state of the disease. Deep learning has emerged as a prominent class of machine learning algorithms in computer vision and has shown successful applications in various medical image analysis tasks.
View Article and Find Full Text PDFImmunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity.
View Article and Find Full Text PDFMotor cortex functional connectivity is associated with underlying neurochemistry in ALS.
J Neurol Neurosurg Psychiatry
March 2023
Article Synopsis
- The study investigates the structural and neurochemical factors affecting motor cortex connectivity in ALS patients compared to healthy controls.
- 52 ALS patients and 52 matched controls underwent various imaging techniques to analyze brain connectivity and motor function.
- Results show that ALS patients had reduced connectivity in the primary motor cortex and altered neurochemical markers, correlating with difficulties in motor tasks like foot tapping.
- The findings suggest that neurochemical indicators, such as N-acetyl aspartate levels, could serve as valuable markers for assessing motor cortex connectivity impairments in ALS.