Publications by authors named "H Bhagat"
Background: A rapid and smooth emergence is essential in patients undergoing trans-sphenoidal pituitary surgeries. Ketofol has been used as an anesthetic agent with good recovery characteristics. We conducted this study to compare the recovery profile of the patients receiving propofol-dexmedetomidine or ketofol-dexmedetomidine infusions for trans-sphenoidal excision of pituitary tumours.
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- - The 2023 International Subarachnoid Hemorrhage Conference stressed the importance of updating strategies for preventing delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage and called for further research in this area.
- - A PubMed search reviewed factors related to DCI prevention, finding that while inhaled anesthetics and antiplatelets show some benefits, more prospective studies are needed on effective anesthetics and antithrombotics.
- - It was recommended to prioritize lumbar drains for cerebrospinal fluid (CSF) diversion, maintain euvolemia during vasospasm, and consider intra-arterial spasmolysis for refractory DCI, with Nimodipine recognized as the
Background And Objective: Early and smooth extubation following anesthesia is an important concern in patients undergoing transsphenoidal pituitary surgery to permit early neurological evaluation and prevent complications. The aim was to compare the RESPONSE FIRST and REVERSAL FIRST techniques for quality of extubation (QOE) in patients undergoing endoscopic transsphenoidal pituitary surgery.
Methods: Fifty-six patients aged 18-60 years, with American Society of Anesthesiologists Physical Statuses I-II, and undergoing transsphenoidal surgery for pituitary tumors were randomized into either the RESPONSE FIRST group, in which neuromuscular reversal was given following the patient's response to oral commands, or the REVERSAL FIRST group, in which reversal of neuromuscular blockade (NMB) was given at the return of spontaneous respiration.
Article Synopsis
- Cerebral vasospasm (CV) is a major complication after subarachnoid hemorrhage from aneurysms, but its molecular causes are not well understood.
- Researchers used RNA sequencing to analyze genes from samples of ruptured intracranial aneurysms (IAs) to find differences between cases with and without vasospasm.
- They identified several dysregulated genes and revealed a pattern of gene expression linked to the progression of aneurysm development and vasospasm, offering new insights for future research in this area.