Publications by authors named "H Beucher"

1,3-Dienes are versatile raw materials for building molecular complexity. We report herein mild conditions for the regio- and stereoselective [only the () isomer obtained] 1,4-carboalkoxylation of 1,3-dienes. This electrochemical multicomponent reaction provides an eco-efficient and straightforward access to a diverse range of ()-polyfunctionalized allyl ether products, without requiring any metal catalyst.

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Article Synopsis
  • - The MITRA-PRO registry shows that evaluating residual mitral regurgitation (MR) using 3D-Vena Contracta Area (VCA) is key for predicting patient survival after mitral valve repairs (TEER).
  • - A study of 823 patients found that lower levels of residual MR (measured by 3D-VCA) correlate with reduced 1-year mortality, establishing 0.07 cm as a critical threshold for patient survival post-procedure.
  • - The findings suggest that 3D-VCA is an effective tool for assessing MR during TEER, with lower residual MR levels associated with better survival outcomes.
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Background: Tricuspid valve transcatheter edge-to-edge repair has emerged as a valuable treatment option for patients with severe tricuspid regurgitation (TR).

Objectives: This study aims to investigate the safety and effectiveness of the PASCAL transcatheter valve repair system in treating severe TR in a real-world patient population.

Methods: The PASTE (PASCAL for Tricuspid Regurgitation-a European registry) study is an investigator-initiated, multicenter, retrospective, and prospective observational cohort analysis conducted across 16 European heart valve centers including consecutive patients treated with the PASCAL transcatheter valve repair system from February 2019 to November 2023.

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