Publications by authors named "H Bekkari"
Objective: Intellectual disability (ID) is considered one of the most common human disorders characterized by significant deficits in cognition and functional and adaptive skills. The aims of this study were to describe the demographic and clinical features of a group of Moroccan individuals with ID living in the Tangier-Tetouan region.
Design: This was a retro-prospective and descriptive exploratory monocentric study realized between November 2020 and August 2023.
Article Synopsis
- Klinefelter syndrome (KS) is a common chromosomal condition in males, typically identified by a 47,XXY karyotype, and can be underdiagnosed; it can also appear as a mosaic karyotype (46,XX/47,XXY) in rare cases.
- The report describes a unique case of a six-month-old infant exhibiting both ovotesticular disorder of sex development (OT-DSD) and a mosaic karyotype, presenting with atypical genitalia including asymmetrical labioscrotal folds and varying reproductive structures.
- The findings reveal a complex interaction between genetics and development, emphasizing the importance of early diagnosis based on atypical genitalia and suggesting that mosaicism should
Background: Differences/disorders of sex development (DSD) encompass a wide range of conditions. Their clinical spectrum and etiological diagnosis have not been reported in Moroccan patients.
Aims: The study aims to highlight the clinical spectrum, etiological diagnosis, and management of patients with DSD.
Plant-derived extracellular vesicles (EVs) have been recognized as important mediators of intercellular communication able to transfer active biomolecules across the plant and animal kingdoms. EVs have demonstrated an impressive array of biological activities, displaying preventive and therapeutic potential in mitigating various pathological processes. Indeed, the simplicity of delivering exogenous and endogenous bioactive molecules to mammalian cells with their low cytotoxicity makes EVs suitable agents for new therapeutic strategies for a variety of pathologies.
View Article and Find Full Text PDFAcute myeloid leukemia (AML) is a heterogeneous and aggressive form of blood cancer characterized by the uncontrolled proliferation of myeloid precursor cells in the bone marrow. It affects individuals of all ages, with incidence increasing notably in those over 65 years old. Despite advancements in treatment, overall survival rates remain unsatisfactory, underscoring the need for a deeper understanding of the disease.
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