Publications by authors named "H Bannazadeh Baghi"
Anal cancer incidence is rising globally, driven primarily by human papillomavirus (HPV) infection. HPV, especially high-risk types 16 and 18, is considered a necessary cause of anal squamous cell carcinoma. Certain populations like people living with HIV, men who have sex with men, inflammatory bowel disease patients, smokers, and those with compromised immunity face elevated risk.
View Article and Find Full Text PDFBackground: The goal of this bioinformatics research is to get a comprehensive understanding of the driver genes and their function in the development, progression, and treatment of cervical cancer. This study constitutes a pioneering attempt, adding to our knowledge of genetic diversity and its ramifications.
Material And Methods: In this project, we use bioinformatics and systems biology methods to identify candidate transcription factors and the genes they regulate in order to identify microRNAs and LncRNAs that regulate these transcription factors and lead to the discovery of new medicines for the treatment of cervical cancer.
MicroRNAs and human viral diseases: A focus on the role of microRNA-29.
Biochim Biophys Acta Mol Basis Dis
January 2025
The viral replication can impress through cellular miRNAs. Indeed, either the antiviral responses or the viral infection changes through cellular miRNAs resulting in affecting many regulatory signaling pathways. One of the microRNA families that is effective in human cancers, diseases, and viral infections is the miR-29 family.
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- * MicroRNAs (miRNAs) play key regulatory roles in viral infections, either promoting or inhibiting these infections, while viruses may also produce their own viral miRNAs (v-miRNAs) to evade host immune responses.
- * This review focuses on the structure, genome, and replication cycle of various viruses, examining how both host miRNAs and v-miRNAs contribute to the pathogenesis of these infections and the potential for new treatment strategies.
Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection is associated with an increased risk of hepatic decompensation, cirrhosis, and hepatocellular carcinoma (HCC). Lactate level, as the end product of glycolysis, plays a substantial role in metabolism beyond energy production.
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