Transcription factors and hormone receptors: Sex‑specific targets for cancer therapy (Review).

Despite advancements in diagnostic and therapeutic technologies, cancer continues to pose a challenge to disease-free longevity in humans. Numerous factors contribute to the onset and progression of cancer, among which sex differences, as an intrinsic biological condition, warrant further attention. The present review summarizes the roles of hormone receptors estrogen receptor α (ERα), estrogen receptor β (ERβ) and androgen receptor (AR) in seven types of cancer: Breast, prostate, ovarian, lung, gastric, colon and liver cancer.

Association Between Home-Base Primary Care and Postdischarge Outcomes Among Older Adults in Korea.

Objectives: This study aimed to evaluate the association between home-based primary care (HBPC) and postdischarge outcomes in Korean older adults.

Design: HBPC was a service that provided medical care by visiting the homes of older adults with limited mobility. In this study, data from the National Health Insurance Service (NHIS) were used, and groups with and without HBPC services were matched 1:1 through propensity score matching.

Effectiveness of the enhanced recovery after surgery (ERAS) program after lobectomy for lung cancer: a single-center observational study using propensity score matching in Vietnam.

Background: Postoperative complications and extended length of stays (LOS) following lobectomy for non-small cell lung cancer (NSCLC) remain significant healthcare and economic burdens, especially in developing countries with limited resources. This study evaluated the effectiveness of enhanced recovery after surgery (ERAS) protocols in addressing these issues.

Methods: This observational study compared two groups of patients, utilizing a prospective arm for ERAS and a retrospective arm for routine care.

Clinical usability and efficacy of a robotic bone fracture reduction system: A pilot animal study.

Challenges in minimally invasive surgeries, such as intramedullary nailing for long bone fractures, include radiation overexposure for patients and surgeons, potential malreduction, and physical burden on surgeons in maintaining the reduction status. A robotic bone fracture reduction system was developed in this study to address these problems. The system consists of a hexapod with six degrees of freedom, with a fracture reduction device and a master device.

Strategy for Enhancing Catalytic Active Site: Introduction of 1D material InSeI for Electrochemical CO Reduction to Formate.

The presence of oxygen vacancies (V) in electrocatalysts plays a significant role in improving the selectivity and activity of CO reduction reaction (CORR). In this study, 1D material with large surface area is utilized to enable uniform V formation on the catalyst. 1D structured indium selenoiodide (InSeI) is synthesized and used as an electrocatalyst for the conversion of CO to formate.