Changes in Inhaled Nitric Oxide Use Across ICUs After Implementation of a Standard Pathway.

Objectives: Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator. It is expensive, frequently used, and not without risk. There is limited evidence supporting a standard approach to initiation and weaning.

Aging varies greatly within a single genus: A demographic study of Rhododendron spp. in botanic gardens.

Premise: There is mounting evidence that age matters in plant demography, but also indications that relationships between age and demographic rates may vary significantly among species. Age-based plant demographic data, however, are time-consuming to collect and still lacking for most species, and little is known about general patterns across species or what may drive differences.

Methods: We used individual birth and death records for 12 Rhododendron species from botanic gardens and conducted Bayesian survival trajectory analyses to assess how mortality changed with age.

Ethical Considerations in Ever-Expanding Utilization of ECLS: A Research Agenda.

Technological advancements and rapid expansion in the clinical use of extracorporeal life support (ECLS) across all age ranges in the last decade, including during the COVID-19 pandemic, has led to important ethical considerations. As a costly and resource intensive therapy, ECLS is used emergently under high stakes circumstances where there is often prognostic uncertainty and risk for serious complications. To develop a research agenda to further characterize and address these ethical dilemmas, a working group of specialists in ECLS, critical care, cardiothoracic surgery, palliative care, and bioethics convened at a single pediatric academic institution over the course of 18 months.

Building a Culture of Wellness When Systems Do Not Allow for Collaborative Care.

Introduction: Health care is fragmented and frustrating to patients and physicians. The consequences include patient and physician dissatisfaction.

Methods: The author's perspective is informed by his research, innovation, and leadership to optimize the experience of care for physicians and patients.

CONNECT Workshops to Enhance Physician and Patient Experience: Interviews Reveal the Physician Perspective.

Introduction: Physicians' relationships with patients are a critical determinant of job satisfaction, and patients who experience compassionate care have better outcomes. The CONNECT workshop at Seattle Children's teaches communication strategies to optimize both patient and physician experience. This article describes participants' experiences during the workshops and the impact on their subsequent behaviors and satisfaction.