Determinants of cognitive dysfunction in adults with sickle cell-related stroke or suspected neurological morbidity.

The prognosis of sickle cell disease (SCD) in adults is determined primarily by damage to targeted organs such as the brain. Cognitive dysfunction in SCD is a common chronic neurological manifestation, but studies remain mostly descriptive in adults. The objective of this study was to better characterize the cognitive profile and the association between cognitive dysfunction and brain lesions.

Bacterial Genetic Approach to the Study of Reactive Oxygen Species Production in During Infection.

Over the last decade, an increasing number of reports presented larvae as an important model to study host-pathogen interactions. Coherently, increasing information became available about molecular mechanisms used by this host to cope with microbial infections but few of them dealt with oxidative stress. In this work, we addressed the role of reactive oxygen species (ROS) produced by the immune system of to resist against , an intracellular pathogen responsible for a wide range of infections.

Ideal Surgical Margin to Prevent Early Recurrence After Hepatic Resection for Hepatocellular Carcinoma.

Backgrounds And Aims: Postoperative early recurrence after hepatic resection for hepatocellular carcinoma (HCC) poses a challenge to surgeons, and the effect of a surgical margin is still controversial. This study aimed to identify an ideal margin to prevent early recurrence.

Methods: A total of 226 consecutive patients who underwent primary curative hepatic resection for solitary and primary HCC were enrolled.