Immediate radical prostatectomy for incidentally found prostate cancer after open prostatectomy for benign prostatic hyperplasia.

We describe the case report and detailed operative findings of a 57-year-old man who underwent radical retropubic prostatectomy (RRP) for incidental prostate cancer 2 weeks after open prostatectomy for benign prostatic hyperplasia (BPH). We advocate an open cystotomy at the time of RRP to identify the ureters and assure that the bladder neck margin is free of prostatic tissue. We offer this therapy as a safe curative treatment modality in the early postoperative period after prior prostate surgery.

Incidence of stool guaiac conversion following extracorporeal shock wave lithotripsy.

Objectives: To study, in a prospective fashion, acute traumatic effects on the gastrointestinal tract of patients treated by extracorporeal shock wave lithotripsy (ESWL).

Methods: Stool samples from each of 54 patients were tested before and after ESWL for conversion to hemoccult positive. A minimum of one negative pre-ESWL stool guaiac test was required for inclusion into the study.

Alteration of the tumor suppressor gene p53 in a high fraction of hormone refractory prostate cancer.

Purpose: We studied the role of p53 tumor suppressor gene alteration in prostate cancer progression by demonstrating a difference in abnormal p53 findings between early and hormone refractory disease.

Materials And Methods: The study included p53 immunohistochemistry of 26 archival transurethral resection specimens from patients with radiation recurrent and hormone refractory disease, 27 untreated primary tumors and 8 untreated metastatic lesions. p53 mutation analysis of tumor deoxyribonucleic acid (DNA) from microdissected specimens was done by cold single strand conformational polymorphism and DNA sequencing.