Publications by authors named "H B Andersen"
is a commercially important tree native to Japan. The tree belongs to the ancient genus and has found important uses as a medicinal plant, as well as a main source of timber in Japan. In recent years, there has been an increased interest in discovering extended uses of as a source of novel bioactive natural products with potential applications as lead compounds for active principles of future drugs.
View Article and Find Full Text PDFThe overall aim of the present study was to determine if exposure to three high volume plastic additives, including diethylhexyl phthalate (DEHP), bisphenol A (BPA) and benzotriazoles (BT), have the potential to promote adverse effects in Atlantic cod (G. morhua). Ex vivo precision cut - liver slices (PCLS) from six male juvenile Atlantic cod were exposed to four concentrations of mono-(2-ethylhexyl)-phthalate (MEHP, the main metabolite of DEHP), BPA and BT both singly and in mixtures ranging from 0.
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- The study investigates neuromuscular junction (NMJ) function in patients with Charcot-Marie Tooth (CMT) disease and explores the potential for improving muscle strength through ClC-1 channel inhibition.
- Results showed significant NMJ abnormalities in CMT patients, such as increased jitter and blocking, which correlated with weaker muscle performance and endurance.
- Preclinical experiments indicated that a new drug, NMD670, improved muscle strength and endurance in CMT mice, suggesting that targeting NMJ dysfunction might offer a new therapeutic approach for CMT patients.
Background And Objectives: Previous studies on incident myasthenia gravis (MG) have shown inconsistent results. In this study, we determined the MG incidence rates (IRs) over a 36-year period to detect potential trends in MG incidence over time and for different age groups.
Methods: In this nationwide population-based study from 1985 to 2021, we identified patients aged 18 and older with a primary MG diagnosis in the Danish National Patient Registry.
Background And Aim: Recent studies have suggested that the incidence rate (IR) and the rate of death (MR) of amyotrophic lateral sclerosis (ALS) are increasing. Still, it remains unclear whether this is due to improved case ascertainment or represents a true increase. We examined the development in the incidence and mortality of ALS in Denmark for 42 years.
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