Antigenicity of the proteins in soy lecithin and soy oil in soybean allergy.

Background: Soy lecithin and soy oil are usually produced from the hexane extract of soybean. Some of the soybean proteins are included in the extract and are therefore present in small amounts in both soy lecithin and soy oil. The antigenicity of the proteins present in defatted soybean has been studied with respect to soybean allergy, but the antigenicity of those found in the extract is yet to be investigated.

Major allergens in soybean and clinical significance of IgG4 antibodies investigated by IgE- and IgG4-immunoblotting with sera from soybean-sensitive patients.

Background: Soybean occasionally causes food allergy but its major allergens have not been sufficiently confirmed. The relationship between food allergy and food-specific IgG4 has also not been defined.

Objective: We investigated the allergenicity of soybean proteins and the clinical significance of soybean-specific IgG4.